What is the most profitable business?
The most profitable business is not easily defined. Profits are dependent on numerous factors, including the state where the business operates, the economic conditions, changes in consumer behavior, and the choices you make as the business owner and operator.
What online businesses are most profitable?
Online businesses are typically a high profit business because it takes little revenue to start up. Although the online small business landscape is continuously changing, current trends show eLearning services (such as online courses and webinars), freelancing, and IT services all have high profit margins.
What kind of businesses make the most money?

Some sectors continue to grow and earn steady profits. The five most profitables businesses are:

  • Software

  • Insurance

  • Healthcare

  • Legal services

  • Accounting

What business has the highest profit margin?
IBISworld names tax preparation software developers as the top industry in 2022 for highest profit margin. Stock and commodities trading is second on the report.


You don’t want to run any business. You want to hit the ground running and create the most profitable small business. By doing so, you’ll stay motivated and eventually duplicate the success with other businesses - further increasing revenue and profit. 

  • Consider online ventures, which require little startup capital and most do not require specialized training or certifications.
  • Develop a small business idea you’re interested and motivated to work with. It will become your main focus, so make it worth your while.
  • Use our list of 20 most profitable small businesses in 2022 for brainstorming and finding the right fit for your skills and lifestyle.
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About the Authors

Sara Coleman

Written by: Sara Coleman

Freelance Financial Writer

Sara Coleman is a freelance writer with several years of experience covering personal finance topics such as insurance, loans, credit cards, budgeting and more. Sara's work has been published across numerous financial sites. She is also a published children's book author.

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Kal Salem

Reviewed by: Kal Salem

CPA, PMP and Finance Consultant

A CPA and finance professional working with small businesses to educate owners and grow alongside their businesses. He holds a Masters in Accounting and a BS in Supply Chain Management. Owner at Salem CPA Services LLC.

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Somer G. Anderson, Ph.D.

Fact checked by: Somer G. Anderson Ph.D., CPA

Accounting and Finance Professor

Somer G. Anderson has been working in the Accounting and Finance industries for over 20 years as a financial statement auditor, a finance manager in a large healthcare organization, and a Finance and Accounting professor at Maryville University.

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